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Epidemiology and Clinical Research
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  1. Home
  2. Programs
  3. Graduate
  4. Epidemiology And Clinical Research
  5. Master of Science

Master of Science

MSCoterm
  • Epidemiology opens in a new tab
Program Minimum Units
45 Units
University Minimum Units
45 Units
Program Length
2 Years
Interests
Public Health, Data and Information Sciences, Helping Others, Design & User Experience
Academic Areas
Medicine, Medicine and Pre-Medicine, Mathematics & Data Sciences

Overview

The Master’s Degree in Epidemiology and Clinical Research provides students with the skills essential to population-based study and patient-oriented clinical research, including epidemiologic methods and statistical analysis. Many students are clinical investigators with an MD or comparable clinical degree, often in the fellowship stages of their training or are already junior faculty members. The program also considers applicants from doctoral programs in the social, behavioral, or biological sciences who are interested in a concurrent master’s degree and wish to apply epidemiologic techniques in their areas of research interest. The program also serves as a rigorous introduction to epidemiology and clinical research for students with baccalaureate degrees or Stanford co-term students (below) who anticipate careers in clinical epidemiology or medicine. Many go on to PhD and MD degrees or pursue careers in public health and other disciplines.

See Epidemiology & Population Health opens in a new tabfor additional information on the MS Epidemiology & Clinical Research program.

Mentors

MS students in the Graduate Program in Epidemiology and Clinical Research have two mentors. Upon entering the program, each student is assigned an academic program advisor, usually a core faculty member. In addition, the student will choose a research mentor. Research mentors are typically members of the Stanford University professoriate but need not be designated as faculty in EPH. For physicians in our graduate programs, this mentor is usually from the discipline of the student’s clinical affiliation. For example, physicians who maintain an affiliation with another university can often arrange to include a research mentor from the other university if the student’s research takes place, in part, at that university. If the research mentor is from EPH, then the same faculty member may serve as both academic program advisor and research mentor with permission of the program director.

The academic program advisor also serves as the student’s methodology mentor and is responsible for advising in the selection of courses, approving a thesis research topic, monitoring the student’s progress through the program, and helping with other program-related issues that may arise. If a student’s thesis research requires additional expertise not covered by those of the methodology or research mentors (e.g., outcomes research or advanced statistical methods), a third mentor may be appointed with the approval of the methodology mentor.

Coterminal Master’s Program

The Department of Epidemiology and Population Health also offers a coterminal Master’s program opens in a new tab in Epidemiology and Clinical Research for current Stanford undergraduates. Students who desire to concentrate in a specific area can participate in one of the track areas (Infectious Diseases, Health Equity and Community-Engaged Research, Global Health ). Coterminal students are enrolled full-time, and courses are ordinarily taken on campus. Graduates of this program are prepared to contribute creatively to basic or applied projects in epidemiology and clinical research. Many go on to PhD and MD degrees or pursue careers in public health and other disciplines.

Requirements

Core Program Requirements

Epidemiologic Methods

Complete all of the following course(s):
EPI 225

Introduction to Epidemiologic and Clinical Research Methods

3 Units
EPI 226

Intermediate Epidemiologic and Clinical Research Methods

3 Units
EPI 251

Design and Conduct of Clinical Trials

3 Units

EPI 251 is recommended but not required for students in designated tracks.

EPI 225 and EPI 226 must be taken for a letter grade and completed with B- or better. A grade lower than B- will require remedial work, or the student may need to retake the course.

Core courses in epidemiologic methods and biostatistics are ordinarily taken during the first year of study.

Biostatistics

Complete all of the following course(s):
EPI 259

Introduction to Probability and Statistics for Epidemiology

3 Units
EPI 261

Intermediate Biostatistics: Analysis of Discrete Data

3 Units
EPI 262

Intermediate Biostatistics: Regression, Prediction, Survival Analysis

3 Units

All courses must be taken for a letter grade and completed with B- or better. A grade lower than B- will require remedial work, or the student may need to retake the course

Research Seminar (3 quarters)

Complete 3 - 3 courses and earn 3 - 3 units in the following course(s):
EPI 236

Epidemiology Research Seminar

1 Units

EPI 236 is not offered in summer.

Research Conduct

Complete all of the following course(s):
MED 255

The Responsible Conduct of Research

1 Units

Research Conduct requirement may be waived for students who are listed as principal investigator for a Stanford IRB-approved research protocol. Students can upload their IRB via MAP opens in a new tab to request the waiver.

Electives

Earn at least 11 units in the following course(s):
BIO 230

Cellular and Molecular Immunology: An Introductory Course

4 Units
BIOE 122

BioSecurity and Pandemic Resilience

2-5 Units
CEE 274

Environmental Microbiology I

3 Units
CEE 274D

Pathogens and Disinfection

3 Units
CEE 274P

Environmental Health Microbiology Lab

3-4 Units
CEE 371C

SARS-CoV-2 in the Environment

3 Units
CHPR 212

Methods for Health Care Delivery Innovation, Implementation and Evaluation

2 Units
CHPR 228

Theoretical Foundations and Design of Behavioral Intervention Trials

3 Units
CHPR 242

The Science of Well-being: A Global Perspective

3 Units
CHPR 247

Pragmatic Skills for Mixed Methods Community Research

3 Units
CHPR 288

Cancer in Asian Americans: Epidemiology and Prevention

2 Units
EARTHSYS 114

Global Change and Emerging Infectious Disease

3 Units
EARTHSYS 214

Global Change and Emerging Infectious Disease

3 Units
ECON 127

Economics of Health Improvement in Developing Countries

5 Units
ENGLISH 102

Pathogens and Populations: Representing Infectious Disease

5 Units
EPI 202

R Fundamentals for Health Research

1-2 Units
EPI 206

Meta-research: Appraising Research Findings, Bias, and Meta-analysis

3 Units
EPI 214

Scientific Writing

2-3 Units
EPI 219

Evaluating Technologies for Diagnosis, Prediction and Screening

3 Units
EPI 223

Introduction to Data Management and Analysis in SAS & R

2-3 Units
EPI 224

Genetic Epidemiology

3 Units
EPI 227

Advanced Epidemiologic Methods

3 Units
EPI 231

Epidemiology of Infectious Diseases

3 Units
EPI 237

Practical Approaches to Global Health Research

1-3 Units
EPI 238

Genes and Environment in Disease Causation: Implications for Medicine and Public Health

2-3 Units
EPI 240

Reproductive and Perinatal Epidemiology

3 Units
EPI 244

Developing Measurement Tools for Health Research

2 Units
EPI 247

Epidemic Intelligence: How to Identify, Investigate and Interrupt Outbreaks of Disease

4 Units
EPI 248

Human Health and the Environment

2 Units
EPI 253

Cancer Epidemiology and Prevention

3 Units
EPI 258

Introduction to Probability and Statistics for Clinical Research

3 Units
EPI 263

Social Epidemiology

2 Units
EPI 264

Foundations of Statistical and Scientific Inference

1-2 Units
EPI 265

Using Real-World Data for Clinical and Population Health Research 

2 Units
EPI 267

Life Course Epidemiology

2 Units
EPI 270

Big Data Methods for Behavioral, Social, and Population Health Research

2-3 Units
EPI 272

The Science of Community Engagement in Health Research

3 Units
EPI 282

Community-Based Participatory Research for Health

3 Units
EPI 299

Directed Reading in Epidemiology

1-18 Units
EPI 297

History of Epidemiology

2 Units
GENE 208

Gut Microbiota in Health and Disease

3 Units
HISTORY 243D

Emerging Diseases, Past and Present

5 Units
HRP 224

Social Entrepreneurship and Innovation Lab (SE Lab) - Human & Planetary Health

1-4 Units
HRP 252

Outcomes Analysis

4 Units
HRP 263

Advanced Decision Science Methods and Modeling in Health

3 Units
HRP 391

Health Law: Finance and Insurance

3 Units
HRP 392

Introduction to Cost-Effectiveness Analysis: Evaluating Benefits and Costs of Health Interventions

4-5 Units
MI 115B

The Vaccine Revolution

5-6 Units
MI 210

Microbe-Host Interactions in Health and Disease

4 Units
MI 221

Gut Microbiota in Health and Disease

3 Units
MS&E 292

Health Policy Modeling

3 Units
PEDS 202A

Practical Applications for Qualitative Data Analysis

3 Units
PEDS 202C

Qualitative Research Methods and Study Design

2-3 Units
SOMGEN 207

Theories of Change in Global Health

3-4 Units

*Any graduate-level EPI course with a primary focus on epidemiology, clinical, or population health or methods can be taken as an elective if approved by the student's epidemiology advisor.

*Please note that EPI 273, Essentials of Clinical Research at Stanford, is for the broader research community and not intended for for matriculated students.

Concentrations

Concentrations are not required. If students would like to take courses in a concentration, please select suggested courses below.

Global Health Concentration

In addition to completing the core courses required for an MS in Epidemiology and Clinical Research, students focusing on Global Health Concentration must complete the following requirements:

Required Course:  EPI 237 opens in a new tab: Practical Approaches to Global Health Research (INTLPOL 290, MED 226)

Electives: Take at least six units from the list below

·       EPI 231: Epidemiology of Infectious Diseases

·       EARTHSYS 214: Global Change and Emerging Infectious Disease (EARTHSYS 114, ESS 213, HUMBIO 114)

·       HRP 252: Outcomes Analysis (BIOMEDIN 251, MED 252)

·       SOMGEN 207: Theories of Change in Global Health (INTLPOL 291, PUBLPOL 291)

Health Equity and Community-Engaged Research Concentration

Health Equity and Community-Engaged Research (THE CeR) is ideal for students with different health equity research interests across the fields of epidemiology, health policy, environmental health, health services research, bioinformatics, and other related fields. Students focusing on Health Equity and Community-Engaged Research must complete the following requirements:

Required Courses:

1. EPI 272: The Science of Community Engagement in Health Research (CHPR 227)

2. EPI 282: Community-Based Participatory Research for Health

3. EPI 299: Directed Reading in Epidemiology (taken for 1 unit with Dr. Rosas, Dr. Rodriguez-Espinosa, or Dr. Thomas)

4. One methods course from the list below:

• EPI 244: Developing Measurement Tools for Health Research

• EPI 270: Big Data Methods for Behavioral, Social, and Population Health Research

• CHPR 212: Methods for Health Care Delivery Innovation, Implementation and Evaluation (HRP 218, MED 212)

• CHPR 228: Theoretical Foundations and Design of Behavioral Intervention Trials

• CHPR 247: Methods in Community Assessment, Evaluation, and Research (MED 247)

• PEDS 202A: Practical Applications for Qualitative Data Analysis

• PEDS 202C: Qualitative Research Methods and Study Design

Note: Additional electives may be approved by the student’s advisor.

Infectious Disease Concentration

The Adult and Pediatric Divisions of Infectious Diseases coordinate an interdisciplinary program in Infectious Diseases for students. In addition to completing the core courses required for an MS degree in Epidemiology and Clinical Research, students focusing on the Infectious Disease Concentration must complete the following requirements:

Required Course: EPI 231: Epidemiology of Infectious Diseases

·       NOT required to take EPI 251: Design and Conduct of Clinical Trials (encouraged, yet not required)

·       Encouraged to attend ID seminars opens in a new tab in the Division of Infectious Diseases

Electives: Take at least 6 units from the list below

·       EPI 237 opens in a new tab: Practical Approaches to Global Health Research (INTLPOL 290, MED 226)

·       EPI 247 opens in a new tab: Epidemic Intelligence (HUMBIO 57)

·       BIO 230: Cellular and Molecular Immunology: An Introductory Course (IMMUNOL 200, MI 200)

·       BIOE 122: BioSecurity and Pandemic Resilience (EMED 122, EMED 222, PUBLPOL 122, PUBLPOL 222)

·       CEE 274: Environmental Microbiology I (BIO 273A, CHEMENG 174, CHEMENG 274)

·       CEE 274D: Pathogens and Disinfection

·       CEE 274P: Environmental Health Microbiology Lab (offered various years)

·       CEE 371C: SARS-CoV-2 in the Environment

·       EARTHSYS 114: Global Change and Emerging Infectious Disease (EARTHSYS 214, ESS 213, HUMBIO 114)

·       ENGLISH 102: Pathogens and Populations: Representing Infectious Disease

·       GENE 208: Gut Microbiota in Health and Disease (BIOE 221G, MI 221)

·       HISTORY 243D: Emerging Diseases, Past and Present

·       MI 115B: The Vaccine Revolution

·       MI 210: Advanced Pathogenesis of Bacteria, Viruses, and Eukaryotic Parasites

·       MI 221: Gut Microbiota in Health and Disease (BIOE 221G, GENE 208)

·       MS&E 292: Health Policy Modeling

Note: Additional Infectious Disease electives may be approved by the student's advisor.

Master's Thesis

Students must take 12 units total over at least two quarters. Only 12 units are counted towards the 45-unit degree requirement.

Complete at least 2 and earn 12 - 12 units in the following course(s):
EPI 399

Graduate Research

1-18 Units

The completion of a master’s thesis is an essential component of the MS degree, allowing students a chance to integrate epidemiologic principles learned in courses. A thesis should demonstrate the following:

•     Familiarity with epidemiologic terms, reasoning, and issues.

•     Ability to communicate scientific reasoning and argue analytically.

•     Awareness of technical, methodological, and other issues relevant to traditional and clinical

epidemiologic research.

•     Comprehension of statistical techniques, their proper use, and limitations.

•     Knowledge in a substantive area.

The thesis is ordinarily 30 to 60 pages long, double-spaced, including tables, figures and references. Each thesis must include a summary abstract of approximately 400 to 800 words. The thesis can take one of the four following forms:

•     Original analysis of data, whether collected primarily for the thesis or as secondary data analysis. (This thesis form is most commonly selected by students.)

•     A comprehensive literature review with a meta-analysis of data or a critical reanalysis of data.

•     Evaluation of a methodologic problem using real or hypothetical data.

•     A comprehensive literature review with a grant proposal (NIH-style format) for a new study to bridge a gap in the existing knowledge. The proposal should highlight methodologic principles.

The quality of the master's thesis should be such that it can be converted into a manuscript for publication or a credible research grant application, and students are strongly encouraged to do so.

Students must present their research findings during a session of EPI 236: Epidemiology Research Seminar.

Please visit Stanford Library opens in a new tab for previously approved Epidemiology and Clinical Research master's theses.

Each student’s thesis committee comprises at least two faculty members, an epidemiology core reader, and a co-reader. The epidemiology core reader, typically the student’s methodology mentor, is the principal thesis advisor. The co-reader is typically the research mentor. The epidemiology core reader is generally a member of the Stanford Academic Council and should be listed as the instructor for at least 9 of the required 12 master’s thesis (research) units (EPI 399).

Registration for master's thesis units must be approved by the core reader. If the student’s thesis research requires expertise beyond that covered by the mentoring team described above, a third faculty mentor may be appointed as a thesis reader. This appointment must be requested by the student and approved by the core reader. Primary supervision during thesis research and writing is shared by the core reader and the co-reader.

Completion of the master's thesis involves registration for at least 12 units of master’s thesis research over a period of two or more quarters. During the first quarter of research, a proposal for the thesis must be submitted to thesis readers when the project is in the early conceptual stages. The purpose is for the student to obtain guidance from the Thesis Committee about specific aims, study design features, and analytic methods before commencing the project. The Master’s Thesis Committee will notify the student of its decision within two weeks of receipt of the proposal. Rejected proposals can be resubmitted before the end of the quarter.

Registration for the second quarter of master’s thesis units can take place only after the successful completion of the first quarter thesis requirements. In the quarter the student expects to graduate, the master’s thesis should be completed and submitted to the readers, allowing sufficient time for readers’ comments and revisions that might be required. A student should expect readers’ comments within two weeks of submission. The final version should be submitted at least two weeks before the end of the quarter. Students must send the PDF, including the signature page, to the Student Services Officer before the thesis submission deadline.