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Chemical and Systems Biology
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  1. Home
  2. Programs
  3. Graduate
  4. Chemical And Systems Biology
  5. Doctor of Philosophy

Doctor of Philosophy

PhD
  • Chemical and Systems Biology opens in a new tab
Program Minimum Units
135 Units
University Minimum Units
135 Units
Program Length
6 Years
Interests
Public Health, Technology, Helping Others, Experimentation & Discovery
Academic Areas
Health Sciences, Medicine and Pre-Medicine

Overview

The Department of Chemical and Systems Biology offers interdisciplinary training to prepare students for independent careers in biomedical science. The program’s primary focus is cell signaling, chemical biology, and systems biology.

The program leading to the PhD degree includes formal and informal study in chemical biology, systems biology, drug discovery, biochemistry, and other areas of relevance to the interests of particular students. First-year students spend one quarter in each of three different laboratories, working closely with other graduate students, a professor, and postdoctoral fellows on various research projects. During the fourth quarter, the student chooses a faculty mentor — based on available positions and the student’s interest — with whom to undertake thesis research. During or before the eighth quarter of study, students must pass a qualifying exam which consists of an oral exam on general knowledge and defense of a research proposal. Course requirements are fulfilled during the first two years of study; the later years of the four- to six-year program are devoted to full-time dissertation research. Close tutorial contact between students and faculty is stressed throughout the program.

Research opportunities also exist for medical students and undergraduates. The limited size of the labs in the department allows for close tutorial contact between students, postdoctoral fellows, and faculty.

The department participates in the four-quarter Health and Human Disease and Practice of Medicine sequence, providing medical students with a comprehensive, systems-based education in physiology, pathology, microbiology, and pharmacology.

Requirements

Program Requirements

Coursework to be completed within the first two years:

Important note: Normally, if a course has the option to be taken as a letter grade, the student must take the course as a letter grade and receive a B- or better to have the course count towards the CSB PhD requirements.

Required Courses

Complete the following courses in Autumn Quarter, Year 1.

Complete all of the following course(s):
BIOS 200

Foundations in Experimental Biology

5 Units
BIOS 204

Modeling Cell Signaling

3 Units
CSB 201

Chemical and Systems Biology Bootcamp

1 Units
CSB 270

Research Seminar

1 Units
CSB 399

Graduate Research

1-18 Units

Additional Required Courses

Complete the following courses in subsequent quarters.

Complete all of the following course(s):
BIOS 242

Writing Compelling Fellowships and Career Development Awards

2 Units
CSB 270

Research Seminar

1 Units
CSB 399

Graduate Research

1-18 Units
MED 255

The Responsible Conduct of Research

1 Units
  • BIOS 242: Applied Grant-Writing Compelling Fellowships and Career Development Awards (Fall and Spring)

    • To be taken once, after selecting a thesis advisor. Students use their Qualifying Exam Proposal and/or skills obtained in this course to apply for fellowships and grants during their time in CSB ( e.g., NIH F31, NSF, etc.). Choose another scientific writing course if you have already secured a fellowship.

  • CSB 270: Research Seminar (Fall, Winter, and Spring)

    • To be taken fall, winter, and spring of years one and two

  • CSB 399: Graduate Research (Fall, Winter, Spring, and Summer)

    • To be taken every quarter until students reach 135 units, at which point students have the option to go to Terminal Graduation Registration status and enroll in CSB 802 for zero units all following quarters until graduation

  • MED 255: The Responsible Conduct of Research (Fall, Winter, or Spring)

    • To be taken once

Chemical Biology

Complete at least 1 of the following courses:
CHEM 281

Synthesis and Analysis at the Chemistry-Biology Interface

3 Units
CSB 260

Concepts and Applications in Chemical Biology

3 Units

If CSB 260 and CHEM 281 are both offered within the same year, you should take CSB 260 for this requirement.

CSB Electives

Complete at least 2 of the following courses:
CSB 221

Methods and Logic in Bioscience Research

4 Units
CSB 240A

A Practical Approach to Drug Discovery and Development

3-4 Units
CSB 240B

A Practical Approach to Drug Discover and Development

3-4 Units
CSB 242

Drug Discovery and Development Seminar Series

1 Units
CSB 245

Economics of Biotechnology

2 Units
CSB 250

The Biology of Chromatin Templated Processes

3 Units

Additional Elective

Complete at least 1 of the following courses:
BIO 294

Cellular Biophysics

3 Units
or
APPPHYS 294

Cellular Biophysics

3 Units
BIOC 224

Advanced Cell Biology

3 Units
or
BIO 214

Advanced Cell Biology

3 Units
or
MCP 221

Advanced Cell Biology

3 Units
BIOC 241

Biological Macromolecules

3-5 Units
or
BIOE 241

Biological Macromolecules

3-5 Units
or
BIOPHYS 241

Biological Macromolecules

3-5 Units
or
SBIO 241

Biological Macromolecules

3-5 Units
BIOS 217

Foundations of statistics and reproducible research

2 Units
BIOS 227

Mass Spectrometry and Proteomics: Opening the Black Box

2 Units
BIOS 446

Metabolism and Metabolic Techniques in Research

2 Units
DBIO 210

Developmental Biology

4 Units
GENE 205

Advanced Genetics

3 Units
SBIO 242

Methods in Molecular Biophysics

3 Units

Other electives are possible with approval from the Student Advisory Committee.

Departmental Milestones:

In addition to the university requirements for the PhD described in Graduate Degrees opens in a new tab, Chemical and Systems Biology has required departmental milestones:

  • The quarterly ethics discussion is required for first and second-year students

  • By the time a student is scheduling their thesis defense, the student’s first-author research article should be accepted for publication